Clinical studies carried out by the UNIVERSITY of PAVIA through Clinical and Instrumental Evaluation of the two formulations, YALODÉ COMPRESSES and YALODÉ INTENSIVE WRINKLE REPAIR have unequivocally demonstrated the Efficacy and Tolerability of the YALODÉ Line products.
Specifically, the 2 clinics performed by dermatologists on a sample of 20 women showed that the anti-aging tablets and face cream, in addition to safety tests on all products in the Line, were well tolerated in 100% of subjects.
CLINICAL/INSTRUMENTAL EVALUATION OF THE MOISTURIZING AND ANTI-WRINKLE EFFICACY OF A DIETARY SUPPLEMENT
SKIN PROFILOMETRY ASSESSMENT
Skin relief was assessed by PRIMOS 3D. It is a 3D scanner that acquires a point cloud in a three-dimensional coordinate system of the object’s surface.
| T30 | T60 | |
|---|---|---|
| Average % change vs T0 | -9,1% | -12,8% |
| T test vs T0 | 0,010 | 0,000 |
| Max (maximum variation) | -34,1% | -35,3% |
| Min (minimum change) | 22,4% | 11,2% |
| % of subjects in whom instrumental reduction in wrinkle depth was recorded (< of -1%) | 65%* | 85%** |
TABLE 1. The table shows the average, minimum and maximum percentage changes in wrinkle depth analyzed after 30 and 60 days of daily product use.
* 13 subjects – ** 17 subjects
COMMENT: After 30 and 60 days of product use, there was a significant improvement in skin roughness (expressed as an average % reduction in wrinkle depth analyzed) of 9.1% and 12.8%, respectively.
NOTE: Intra-group statistical analysis (vs. T0) is shown in the graph.
LEGEND:
*** ,p<0.001
** ,p<0.01
* ,p<0.05
ASSESSMENT OF SKIN HYDRATION
Hydration measurement is based on the internationally recognized CORNEOMETER® method (Courage+Khazaka electronic GmbH).
COMMENT: After 30 and 60 days of product use, there was a significant improvement in skin hydration of 9.6 percent and 17.4 percent, respectively (mean values).
NOTE: Intra-group statistical analysis (vs. T0) is shown in the graph.
LEGEND:
*** ,p<0.001
** ,p<0.01
* ,p<0.05
Conclusions:
CLINICAL/INSTRUMENTAL EVALUATION OF THE MOISTURIZING AND
ANTI-WRINKLE EFFICACY OF A COSMETIC PRODUCT
CUTAN ELASTICITY ASSESSMENT
Evaluation of the R2 PARAMETER through the MPA 580 CUTOMETER.
COMMENT: The product results, at all monitored experimental times, in a statistically significant (p<0.001) increase in skin elasticity.
NOTE: Above the error bar is the intra-group statistical analysis (vs. T0).
LEGEND:
*** ,p<0.001
SKIN PROFILOMETRY ASSESSMENT
| T30 | T60 | |
|---|---|---|
| Average % change vs T0 | -9,0% | -15,3% |
| T test vs T0 | 0,001 | 0,000 |
| Max (maximum variation) | -28,8% | -37,5% |
| Min (minimum change) | 2,1% | 3,1% |
| % of subjects in whom instrumental reduction in wrinkle depth was recorded (< of -1%) | 75%* | 85%** |
* 15 subjects – ** 17 subjects
COMMENT: The product results, at all monitored experimental times, in a statistically significant (p<0.001) reduction in wrinkle depth analyzed.
NOTE: Intra-group statistical analysis (vs. T0) is shown in the graph.
ASSESSMENT OF SKIN HYDRATION INDEX
COMMENT: The product results, at all monitored experimental times, in a statistically significant (p<0.001) increase in skin hydration.
NOTE: Above the error bar is the intra-group statistical analysis (vs.T0).
LEGEND:
*** ,p<0.001
Conclusions:
Increased skin elasticity (parameter R2) after both 30 days (+7.0%) and 60 days (+10.7%) of use;
Improvement in the profilometric parameter analyzed (reduction of wrinkle depth in the periocular area) after both 30 days (-9.0%) and 60 days (-15.3%) of use;
Increased skin hydration after both 30 days (+21.2%) and 60 days (+25.8%) of use.
The beating heart of Italian Skin Care meets research and scientific innovation to formulate nutraceuticals and cosmeceuticals-high in active ingredients and high in bioavailability-capable of promoting skin rejuvenation from within.
Monday to Friday
08:30–12:30 / 13:30–17:30 (Italian time zone)
Mail: info@sialormilano.it
© 2024, Sialor Milan – Designed by Red Velvet Studio Srl
