Hyaluronic Acid

Naturally occurring in our bodies, Hyaluronic Acid was discovered in 1934 within bovine vitreous humor, but it was not until 1954 that its composition and chemical structure was fully delineated.

Hyaluronic Acid is a natural molecule that is totally Biocompatible, immunogenic and free of toxicity and has important applications in the COSMETIC-ESTETIC, osteoarticular, surgical, and tissue repair fields.

Its greatest expression is found at the level of the skin in that, having the unique ability to retain water, it is able to moisturize and consequently plump the tissues.

Properties Hyaluronic Acid

The molecule with a thousand properties

With the passage of time, collagen regeneration is increasingly reduced contributing to the formation of classic signs of aging such as fine lines, forehead wrinkles, crow’s feet, neck wrinkles, etc.

Precisely because of its filling, volumizing, anti-reddening, and anti-aging power, Hyaluronic Acid is increasingly being used in the formulations of aesthetic medicine products such as fillers and cosmetics.

SIALOR uses Hyaluronic Acid in all of its beauty products from fillers to cosmetics, choosing to include this extraordinary molecule in its revolutionary FOOD INTEGRATOR YALODE’ COMPRESSES as well.

Yalodé Triple Layer Tablets

The tablets were developed in triple-layer, patented process in order to improve the stability and absorption of Hyaluronic Acid to provide results that deeply stimulate the cellular metabolism of skin tissues, from within, which cannot be achieved by creams alone.

Molecular Weight of Hyaluronic Acid

The surprising new feature is the Molecular Weight of the Hyaluronic Acid contained in the tablets, in fact it is High Molecular Weight Hyaluronic Acid.

Why is there talk of novelty?

Because most skin supplements are based on hydrolyzed Collagen with the addition of small amounts of Hyaluronic Acid whose origin and molecular weight are almost never expressed.

Yalodè Tablets is based on High Molecular Weight Hyaluronic Acid (1 M Da to over 2 M Da) of Biotechnological origin and being NOT bound to Protein can be declared as vegetarian/vegan.

The importance of Molecular Weight is along with origin, the distinguishing feature of Quality and Effective Hyaluronic Acid.


In fact, it is emphasized in scientific literature that endogenous and native Hyaluronic Acid is High Molecular Weight and therefore functional for health.

Of the rest, it has been observed that 500,000 Da is the CUT OFF Molecular Weight for the different properties of Hyaluronic Acid and that therefore low and very low Molecular Weight fragments have pro-inflammatory and catabolic properties, in different biological systems.

At present, moreover, there is no scientific evidence demonstrating diffusion and concentration of low or very low Molecular Weight Hyaluronic Acid in organic tissues.

High Molecular Weight Hyaluronic Acid, on the other hand, is actually absorbed and diffuses into the Connective Tissue after a single oral administration as amply demonstrated in the scientific literature.

Yalodé Triple Layer Tablets

High Molecular Weight Hyaluronic Acid Tablets

The dietary supplement Yalodé Tablets has undergone GASTRIC HYDROLISIS to understand the amount of Hyaluronic Acid that is actually hydrolyzed. In fact, it has been observed that only 30 percent of the High Molecular Weight Hyaluronic Acid in the tablets hydrolyzes.

The clinical study at the University of Pavia showed that taking one tablet per day of Yalodé Tablets can improve the profilometric parameter by reducing the depth of wrinkles and increasing the hydration index of the skin.